Age-related macular degeneration

Age-related macular degeneration

Prevent the loss of vision through age-related macular degeneration (AMD)

To the vitamins and micronutrients

What is AMD exactly and how can I prevent it?

Age-related macular degeneration (AMD) is a usually insidious illness at the centre of the retina. This yellow spot (the macula) is the area of the retina with which we can see objects the sharpest. AMD is one of the most frequent causes of a severe vision impairment. The treatment depends on the stage and type of illness.

Key information on macular degeneration

  • Prevalence and causes of AMD

    The precise causes of age-related macular degeneration are not yet fully understood. According to the latest findings, metabolic products are deposited on the macula and damage the photoreceptors over time as the individual gets older. This gradually decreases the visual acuity at the centre of the field of vision. A German study found that the risk of AMD increases with age: around 3.8 per cent of those aged 35 to 44 showed signs of AMD, compared to 24.4 per cent of those aged 65 to 74.

  • Typical symptoms of AMD

    Due to the increasing loss of vision at the centre of the field of vision, objects in the actual focus often appear blurred or distorted. Initially there may also be the impression of a shadow above the focused object. In such cases, persons suffering from AMD often orient themselves based on the perception in the periphery of their field of vision and differences in brightness.

  • How does the illness proceed?

    Macular degeneration proceeds in various stages: early, intermediary and advanced AMD. On average, it takes around ten years for the illness to develop from the early to the late stage, with progression varying considerably from one person to another. The early stage only causes limited restrictions to daily life: the central vision area is perceived as shadowy or blurry. However, due to the diminished eye sight, patients suffering from an advanced stage can occasionally neither recognise faces nor read print.

  • How does ‘wet’ AMD differ from ‘dry’ AMD?

    Macular degeneration exists as a ‘wet’ or ‘dry’ form. Dry AMD accounts for 85 per cent of cases and may develop into the wet variant. Dry AMD is also described as geographic atrophy as there is a partial loss of photocells (atrophy) in its course. It is caused by accumulations of metabolic products underneath the retina that increasingly impede the supply of nutrients to the photocells. The gradual loss of cells usually commences in the macula as the photocells are especially active here.

    Wet AMD is also known as ‘neovascular AMD’. In this form of the illness new blood vessels are formed in the damaged portion of the eye to counter the decreased oxygen supply caused by the illness. The newly formed blood vessels can cause swelling or even haemorrhaging of the macula. Wet AMD proceeds much faster than the dry form.

  • Can AMD be treated with medication?

    The wet form of macular degeneration can be treated with medication. So-called VEGF inhibitors are used, which are intended to prevent additional blood vessels from proliferating in the retina. In addition, they cause the blood vessels that already impair the vision to regress. The medications are repeatedly injected in the eye with local anaesthesia. Today, the wet form of macular degeneration can be arrested for an extended period of time and vision preserved with regular injections of VEGF inhibitors.

    For the dry form of AMD there are specially balanced micronutrient combinations that can help increase the supply of nutrients to the eye.

  • Which micronutrients are helpful for macular degeneration?

    In a series of studies it was found that specific combinations of vitamins and micronutrients can help lower the risk of progressing AMD. These include anti-oxidants such as vitamins C and E that protect the sensitive photocells in the yellow spot of the eye.

    Carotenoids have a high anti-oxidant effect. The two carotenoids lutein and zeaxanthin are found mainly in the retina and the macula and protect these structures. While vegetables such as spinach, cabbage or broccoli contain carotenoids, the quantities present are often insufficient to ensure an adequate supply.

    Zinc is also one of the micronutrients that help protect cells from oxidative stress. Zinc is administered in combination with copper to prevent copper deficiency.

  • Are there further ways of decreasing the risk of AMD?

    In addition to a sufficient supply of vitamins and minerals smoking should be avoided. Many studies identified smoking as a high risk factor for the development of AMD and other eye illnesses. Therefore, not smoking can help prevent AMD or minimise the chances of the condition worsening.

Help with age-related macular degeneration

OmniVision offers you an extensive range of products with different vitamin and mineral combinations that are matched to different needs. Depending on the product, they consist of capsules, granules or tablets. The two products CentroVision® AMD and CentroVision® AMD Premium for example, contain the nutrient combination also used in the AREDS2 study. This study demonstrated that these vitamins and minerals can lower the risk of progression of AMD. Other products are suitable for supporting the eyesight.

CentroVision® AMD

Capsules for diet management for patients with age-related macular degeneration

  • For intermediate and advanced age-related macular degeneration
  • The combination of active ingredients was selected based on medical studies (AREDS2 compliant)
  • Use of brand-name raw materials, such as FloraGLO® and ZeaONE®

CentroVision® AMD Premium

Innovative 3-layer tablet for diet management with age-related macular degeneration

  • For intermediate and advanced age-related macular degeneration
  • The combination of active ingredients was selected based on medical studies (AREDS2 compliant)
  • Innovative 3-layered tablet, so-called MultiARS™ for layer-specific release of the individual active ingredients in the body

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